| abstract |
The present invention relates to MEK inhibitor N- {3- [3-cyclopropyl-5- (2-fluoro-4-iodo-phenylamino) 6,8-dimethyl-2,4,7-trioxo-3,4 New combination comprising 6,7-tetrahydro-2H-pyrido [4,3-d] pyrimidin-1-yl] phenyl} acetamide or a pharmaceutically acceptable salt or solvate thereof with an mTOR inhibitor , Pharmaceutical compositions comprising the same, and methods of using such combinations and compositions in the treatment of conditions where inhibition of MEK and / or mTOR is beneficial, such as cancer. |