http://rdf.ncbi.nlm.nih.gov/pubchem/patent/KR-20120115913-A
Outgoing Links
Predicate | Object |
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assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_7fd15d8ebb22202b5cfe2b109cd922c5 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-16 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K41-0038 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-56 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-16 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-10 |
filingDate | 2011-04-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_85a172e673fbbfb7095c96150e258ed5 |
publicationDate | 2012-10-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | KR-20120115913-A |
titleOfInvention | Radiotherapy sensitizer composition for treating cancer cells, comprising brg-1 derived bromodomain or fragment thereof or nucleic acid codinig the sames |
abstract | The present invention includes a bromodomain derived from BRG-1 or a fragment thereof having a binding activity to an acetylated histone as an active ingredient, a radiation sensitive composition for cancer cell radiation therapy; And an isolated nucleic acid encoding a fragment having a binding activity to a bromodomain or an acetylated histone derived from BRG-1 or a vector having the nucleic acid as an active ingredient, the radiation sensitive composition for cancer cell radiotherapy. . When the BRG-1-derived bromodomain or fragment thereof according to the present invention is present in cancer cells, when irradiated with gamma radiation, not only radiation-sensitive cancer cells but also radiation-resistant cancer cells increase radiation sensitivity to promote cell death. You can. |
isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2019132610-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11345729-B2 |
priorityDate | 2011-04-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 755.