| abstract |
The present invention provides a monoclonal antibody that specifically recognizes CD27 including an O-linked sugar chain to which galactose is not bound and binds to the extracellular domain, and a method of using the same. According to the present invention, a monoclonal antibody or the antibody fragment which specifically recognizes CD27 including an O-linked sugar chain to which galactose is not bound and binds to the extracellular domain, a hybridoma producing the antibody, DNA encoding the antibody, a vector containing the DNA, a transformant obtained by transforming the vector, an antibody or method for producing the antibody fragment using the hybridoma or transformant, and the antibody or antibody fragment The diagnostic agent or therapeutic agent of the disease which CD27 containing as an active ingredient can be provided. |