http://rdf.ncbi.nlm.nih.gov/pubchem/patent/KR-20120113207-A
Outgoing Links
Predicate | Object |
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assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_4cabb775ed8b2e3f4fe71aab411e4842 |
classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L2430-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B33Y80-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L2400-12 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L27-42 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L31-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L31-086 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L27-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L31-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L31-026 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L31-123 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L27-32 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L27-50 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L24-0063 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L27-425 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61L27-32 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61L31-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61L31-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61L27-42 |
filingDate | 2010-06-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a663ca93eb8dbc6382f41b787bf2c551 |
publicationDate | 2012-10-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | KR-20120113207-A |
titleOfInvention | Bone substitute material |
abstract | FIELD OF THE INVENTION The present invention relates to biphasic calcium phosphate / hydroxyapatite (CAP / HAP) bone substitute material, which comprises at least one uniform of a sintered CAP core and a nanocrystalline HAP deposited on top of the sintered CAP core. It includes a closed epitaxial growth layer, which epitaxially grown nanocrystals have the same size and morphology as human bone minerals, ie, lengths of 30 to 46 nm and widths of 14 to 22 nm. The present invention also relates to a method for preparing the CAP / HAP bone replacement material described above, which method comprises the steps of: a) preparing a sintered CAP core material, and b) converting the CAP to HAP. To immerse the sintered CAP core material in an aqueous solution at a temperature of 10 ℃ to 50 ℃ to form a uniform, closed epitaxial growth layer of nanocrystalline hydroxyapatite on the surface of the sintered CAP core material, epitaxial growth The nanocrystals have the same size and morphology as the human bone minerals, and c) separating the solid material from the aqueous solution, although there is a uniform, closed coating of at least one nanocrystalline layer of HAP but before the conversion process is complete. Stopping the conversion, and d) optionally sterilizing the separated material formed from step c). The present invention also relates to a method of using the aforementioned CAP / HAP as an implant or prosthesis for bone formation, bone regeneration, bone healing and / or bone replacement at a defect site of a human or animal. |
priorityDate | 2009-06-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 39.