abstract |
The present invention provides a sulfamide derivative having a adamantyl group represented by the following formula (1) or a pharmaceutically acceptable salt thereof. The sulfamic polyimide derivatives are useful in the treatment of 11 beta-hydroxy steroid dehydrogenase type now 1 (11 β -hydroxysteroid dehydrogenase type1, 11 β -HSD1) various diseases by inhibiting the activity mediated by the 11 β -HSD1 . Formula 1 |