| abstract |
The present invention relates to novel oxazolidinone derivatives represented by the general formula (1), in particular novel oxazolidinone compounds having cyclic amidoxime or cyclic amidazone groups. (One) Wherein R and Q are as defined in the detailed description of the invention. The present invention also relates to a pharmaceutical composition for antibiotics containing a novel oxazolidinone derivative of Formula 1, a prodrug thereof, a hydrate thereof, a solvate thereof, an isomer thereof, and a pharmaceutically acceptable salt thereof as an active ingredient. The novel oxazolidinone derivatives, prodrugs thereof, hydrates thereof, solvates thereof, isomers thereof and pharmaceutically acceptable salts thereof according to the present invention have a broad antimicrobial spectrum, low toxicity, gram positive and gram resistance to resistant bacteria. Since it shows strong antibacterial effect against negative bacteria, it can be usefully used as an antibiotic. |