| abstract |
Compounds, pharmaceutical compositions having these compounds, and casein kinase 1 (eg, CK1γ), casein kinase 2 (CK2), Pim 1, Pim2, Pim3, TGFβ pathway, Wnt pathway, JAK / STAT pathway, and And / or the use of compounds and compositions as mTOR pathway modulators. Also at least in part by abnormal physiological activity of casein kinase 1 (eg CK1γ), casein kinase 2 (CK2), Pim 1, Pim2, Pim3, TGFβ pathway, Wnt pathway, JAK / STAT pathway, and / or mTOR pathway Uses for the treatment or prevention in the area of therapeutic application resulting are disclosed. |