abstract |
Synthetic methods for preparing deoxycholic acid and intermediates thereof, deoxycholic acid synthesized in high purity, compositions and methods of use are provided. Also provided are methods of synthesizing 12-keto or 12-α-hydroxysteroids from Δ-9,11-ene, 11-keto or 11-hydroxy-β-steroids. The invention also relates to new compounds prepared during synthesis. The present invention also relates to the synthesis of deoxycholic acid starting from hydrocortisone. |