http://rdf.ncbi.nlm.nih.gov/pubchem/patent/KR-20120101362-A
Outgoing Links
Predicate | Object |
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assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_c72d118f5664072de841f9c5c34b9d99 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K49-1857 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K49-186 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K49-1842 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K49-0428 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K49-18 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-16 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K49-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B82Y5-00 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K49-18 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-16 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K49-04 |
filingDate | 2010-10-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_12672dc1b93ccd6f647f9f30ae0066e2 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_df75d1ce6ecca4c7271cdb6f6a5e7dad http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5f24368408c12941ae66cd1ae07a9947 |
publicationDate | 2012-09-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | KR-20120101362-A |
titleOfInvention | Treatment of water-insoluble nanoparticles with hydrophilic alpha-hydroxyphosphonic acid conjugates, thereby modifying nanoparticles and their use as contrast agents |
abstract | The present invention relates to water-insoluble nanoparticles, particularly alpha-hydroxy having a hydrophilic moiety that makes nanoparticles of metals and metal compounds useful for diagnostic imaging, such as MR and X-ray imaging, to a sufficient degree of hydrophilicity for use in diagnostic imaging. A method of treating with a phosphonic acid conjugate. Examples of the modified hydrophilic nanoparticles according to the present invention include those in which the hydrophilic moiety of the conjugate used in the modification is an ethylene oxide-based polymer, a copolymer and a zwitterion, and the nanoparticles are superparamagnetic iron oxide and tantalum oxide. It consists of a transition metal oxide such as. The present invention provides nanoparticles having sufficient hydrophilicity to form stable aqueous colloidal suspensions. In addition, diagnostic imaging such as MR and X-rays using the modified hydrophilic nanoparticles as contrast agents is provided. |
isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/KR-20150024850-A |
priorityDate | 2009-10-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 87.