| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_38f6403d850a1fe9e34ef7fd5a010318
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_8e071d18fea054bf8d1420d483e78ed1 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P1-18
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D239-94
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D239-88
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D239-93
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D401-12
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-517
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D471-04
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D405-12
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D417-12
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-02
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P43-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P29-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-28
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P31-12
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P31-04
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P31-00 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-517
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D239-94
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D471-04 |
| filingDate |
2010-07-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3df91c257e3bd93d574c0efbc8e74018
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_2281eb1af0f25c32e0151a348d3f6023
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_89e4e8d995754662297391f7af96c464
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_dc00b0e459e86c690935df83c07a4295 |
| publicationDate |
2012-09-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
KR-20120100886-A |
| titleOfInvention |
Efficacy of Small Molecule Inhibitors of Autophagy and Methods of Use thereof |
| abstract |
Certain aspects of the present invention relate to small molecule autophagy inhibitors and their use for treating and preventing cancer and acute pancreatitis. As disclosed herein, small molecule inhibitors of autophagy have been identified from image-based screens in known bioactive libraries. Such autophagy inhibitors have been found to act by promoting degradation of the type III PI3 kinase complexes required to initiate autophagy. Small molecule autophagy inhibitors with improved efficacy and selectivity have been obtained from medical chemistry studies. |
| priorityDate |
2009-07-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |