| abstract |
The pharmaceutical capsule is a pharmaceutically acceptable excipient in the capsule shell, which is at least one for at least one phospholipid selected from the group consisting of (a) at least one phospholipid, (b) glycols, glycerides and mixtures thereof Solubilizers of ABT-263 or a pharmaceutically acceptable salt thereof in a substantially non-ethanol carrier comprising (c) at least one non-phospholipid surfactant and (d) at least one sulfur-containing antioxidant. A shell encapsulating the solution. Such capsules are useful in the treatment of diseases (eg cancer) characterized by overexpression of one or more anti-apoptotic Bcl-2 family proteins. |