| abstract |
The present invention relates to an oxime derivative of Formula 1, a preparation method thereof, a pharmaceutical composition comprising the same and a method of using the same. In particular, the oxime derivatives according to the invention may act as GPR119 agonists that promote the secretion of GLP-1 and increase insulin secretion for the treatment of type 2 diabetes, complications of diabetes, obesity, dyslipidemia or osteoporosis. Can be. [Formula 1] Wherein RA, RB, n, Ar, A, B, R1 and R2 are as defined in the specification. |