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filingDate 2007-05-17-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_bfcf03231f85243a87d27a3553e729d2
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publicationDate 2012-08-22-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber KR-20120093306-A
titleOfInvention RNA-mediated inhibition of tumor necrosis factor α-related symptoms
abstract The present invention provides RNA interference to silence TNFα cell surface receptor TNF receptor-1 (TNFR1) mRNA expression or to inhibit tumor necrosis factor α (TNFα) by silencing TNFα converting enzyme (TACE / ADAM17) mRNA expression. do. Silencing the TNFα target is particularly useful for treating patients with or at risk of developing TNFα-related symptoms such as dry eye, allergic conjunctivitis, or eye inflammation, or dermatitis, rhinitis, or asthma. Do.
isCitedBy http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2019060613-A3
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priorityDate 2006-05-19-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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