| abstract |
The present invention relates to compositions and methods relating to sampling of biopolymers, in particular fractional sampling of biopolymers. According to one aspect of the invention, embodiments generally relate to unique biopolymer species, wherein the fraction of each biopolymer species contains a cleavable linker. In some embodiments of the invention, the biopolymer species may be attached to the surface. For example, the biopolymer species can be attached to the beads. In some embodiments of the invention, some of the unique biopolymer species can be sampled by cleaving cleavable linkers. In some cases, the sample can be analyzed to determine the sequence of the biopolymer. |