abstract |
The present invention provides a novel fluoro-substituted 3,5-dicyano-4- (1 H -indazol-5-yl) -2,6-dimethyl-1,4-dihydro having protein tyrosine kinase inhibitory activity Pyridine derivatives, methods for their preparation and their use in the treatment of c-Met-mediated diseases or c-Met-mediated conditions, in particular cancer and other proliferative disorders. |