| abstract |
The present invention is to prepare a poly (amino oxalate) PAOX (oxalyl chloride), 1,4-cyclohexanedimethanol (1,4-cyclohexanedimethanol) and piperazinediethanol (poly (amino oxalate)) to the microspheres PAOX according to the present invention is a polymer having three characteristics such as biodegradability, biocompatibility, and cationicity at the same time, and having appropriate hydrophobicity, which leads to rapid release of drugs. In addition, the microspheres may be useful as drug carriers in treating acute inflammatory diseases such as acute liver failure and acute pneumonia by improving intracellular delivery efficiency of drugs. |