| abstract |
The present invention relates to a method for preparing an [ 18 F] organofluoro compound, and more particularly, in the nucleophilic [ 18 F] fluorination reaction as in Scheme 1 below, the base of Formula 1 is used in a solid state. It provides a method for producing an [ 18 F] organofluoro compound. [Reaction Scheme 1] [Formula 1] M n A m According to the present invention, by using a base represented by the formula (1) in a solid state to induce a heterogeneous nucleophilic [ 18 F] fluorination reaction to maintain a minimum base concentration in the solution to provide a method for significantly inhibiting side reactions do. |