| abstract |
The present invention relates to a composition for preventing and treating neuropathic pain containing ginsenosides Rb1 and Rg3, Compound K, or ginseng-derived saponin extract as an active ingredient, specifically, ginsenosides Rb1 and Rg3, Compound K, or Ginseng-derived saponin extracts have been shown to inhibit the pain caused by central nerve damage, peripheral nerve damage, and inflammation. These pain-inhibiting effects are mediated by estrogen receptors and also pain-related factors in the spinal cord microglial cells. It acts by inhibiting expression. |