| abstract |
The present invention provides N- (5-t-butyl-isoxazol-3-yl) -N '-{4- [7- (2-morpholin-4-yl-ethoxy) imidazo [2,1-b ] [1,3] benzothiazol-2-yl] phenyl} urea or a pharmaceutically acceptable salt, solvate, hydrate or polymorph thereof. N- (5-t-butyl-isoxazol-3-yl) -N '-{4- [7- (2-morpholin-4-yl-ethoxy) imidazo [2,1-b] [1 , 3] benzothiazol-2-yl] phenyl} urea is useful for treating, preventing and / or managing diseases or disorders, including but not limited to proliferative diseases, FLT-3 mediated diseases and cancers. N- (5-t-butyl-isoxazol-3-yl) -N '-{4- [7- (2-morpholin-4-yl-ethoxy) imidazo [2,1-b] [1 , 3] benzothiazol-2-yl] phenyl} urea is represented by the following structure: Formula I |