| abstract |
6-amino quinazoline or 3-cyano quinoline derivatives, methods for their preparation and pharmaceutical uses are described. Specifically, the present invention relates to novel 6-amino quinazoline or 3-cyano quinoline derivatives or tautomers, enantiomers, diastereomers, racemates or pharmaceutically acceptable salts thereof represented by general formula (I), Or metabolites, metabolic precursors or prodrugs, and in particular their use as therapeutic agents as protein kinase inhibitors, wherein the respective substituents of formula (I) are as defined herein. |