| abstract |
The present invention provides a substituted amide of formula (I) which is useful as an active ingredient in a pharmaceutical composition, especially a pharmaceutical composition for the treatment of diseases caused by lysophosphatidic acid (LPA). (Wherein A is optionally substituted aryl, B is optionally substituted aromatic 5-membered heterocyclic group, X is single bond or- (CR X1 R X2 ) n- , n is 1, 2, 3 or 4, R X1 , R X2 is hydrogen, Y 1 to Y 5 is CR Y or N, R Y is hydrogen, R 1 and R 2 are hydrogen, and m is 1, 2 or 3 , R 3 represents hydrogen, etc., R 4 represents lower alkyl etc. which may be substituted.) |