abstract |
A compound I is disclosed having the formula represented by formula I: (I) The compounds can be prepared as pharmaceutical compositions and can be used in a variety of diseases in mammals, including humans, including but not limited to inflammatory diseases, autoimmune diseases, proliferative diseases, graft rejection, diseases involving disorders of cartilage conversion, congenital It can be used for the prevention and treatment of diseases associated with cartilage malformations and / or hypersecretion of IL6. |