http://rdf.ncbi.nlm.nih.gov/pubchem/patent/KR-20120056615-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_fa5d97928d5c303b11f7bb2aeb6377ad |
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q2600-158 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-6884 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-6893 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-15 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-68 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-1135 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-68 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-68 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-15 |
| filingDate | 2010-11-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ab392a35a891ac250b01a724c4c40bc0 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_be82d466b9a292380cebc6ad18cbe3bd |
| publicationDate | 2012-06-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | KR-20120056615-A |
| titleOfInvention | Cell proliferation susceptibility markers comprising an APRIN gene or an expression protein thereof or a protein regulated by the reduction of the gene expression |
| abstract | The present invention relates to a cell proliferation susceptibility marker comprising the APRIN gene or its expression protein, or a protein regulated by decreasing the expression of the gene and its medical use, wherein cell proliferation increases when the expression level of the APRIN gene decreases. APRIN gene or its expression protein, or the APRIN gene expression by revealing the increase in cyclin D1, cyclin D3 and phosphorylated ERK1 / 2 (pERK1 / 2) in accordance with the decrease in the amount of expression of the APRIN gene to cause such cell proliferation Cyclin D1, Cyclin D3, and phosphorylated ERK1 / 2 (pERK1 / 2), which are proteins whose expression is increased by decrease, are used as markers for assessing cell proliferation susceptibility in cancer cell lines while diagnosing various cancer diseases such as lung cancer or osteosarcoma. Can also be used. |
| priorityDate | 2010-11-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 597.