Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_3f4508d36cd90890103c299ac719aada |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2015-8527 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A01K2267-025 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A01K2227-108 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-8509 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A01K67-0278 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-85 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-54 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A01K67-027 |
filingDate |
2010-11-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e34c2d99f750aa205a85eda2056a9ffe http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0efa4f4704a59c5587ff4c90bfec6026 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d4b8eb19557e26b97520637eb20e1422 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c5dba20658944fee740e433ce429c1e2 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_59af5033a081dfc3b37cf6d61a51757b http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9f4a6a3beb91da1347985cd1c8abbb7d http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9e9059a32d92252ae056124c42cf10e7 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_00e98172a8d44509630d9828e0a3a89b http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_35e4fb5d371491e690f921685379a5f3 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d28d04d1a1899e630d5d624213b3b7a4 |
publicationDate |
2012-05-31-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
KR-20120055409-A |
titleOfInvention |
Gene targeting knock-in vectors comprising protein overexpression cassettes, methods for their preparation and transgenic cloned animals for cross-transplantation into which the vectors are introduced |
abstract |
The present invention relates to a method for producing a gene targeting vector containing a protein overexpression cassette and a transgenic cloned animal for cross-transplantation into which the vector is introduced. According to the present invention, it is possible to select a promoter according to the purpose of use, thereby controlling expression of a gene for overexpression, and effectively knocking out the alpha 1,3-galactosyltransferase gene and simultaneously overexpressing human CD46 (MCP). Since the cassette is knocked over to be expressed by the selected promoter, it is possible to produce a transgenic cloned miniature cloned pig with suppressed transplant rejection reaction, and using these and their progeny can be widely used for transplantation of intercellular cells and organs. have. |
isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/KR-20170137275-A |
priorityDate |
2010-11-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |