abstract |
The present invention relates to a thermoformed pharmaceutical dosage form having a breaking strength of 300 N or more, wherein the dosage form Opioids (A), Physiologically acceptable free acid (B) in an amount of 0.001 to 5.0% by weight, based on the total weight of the pharmaceutical dosage form and A polyalkylene oxide (C) having a weight average molecular weight (M w ) of at least 200,000 g / mol. |