| abstract |
The present invention relates to novel triazolo [4,3-a] pyridine derivatives of formula (I) wherein all radicals are as defined in the claims: The compounds according to the invention are metabolic glutamate receptor subtypes useful for the treatment or prevention of neurological anc psychiatric disorders associated with glutamate dysfunction and diseases involving the mGluR2 subtype of the metabotropic receptor. It is a positive allosteric modulator of 2 (metabotropic glutamate receptor subtype 2) ("mGluR2"). The invention also relates to pharmaceutical compositions comprising such compounds, methods of preparing such compounds and compositions, and the use of such compounds for the prevention or treatment of neuropsychiatric diseases involving mGluR2. . |