http://rdf.ncbi.nlm.nih.gov/pubchem/patent/KR-20120034167-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_ca61e4db63122e1293d328faa02cc379 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-4436 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P17-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-381 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D409-12 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N5-071 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-381 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D409-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-4436 |
| filingDate | 2010-06-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_caf42ec959570bdc861d257c2360220a http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_38ce737f59a883aa5a6daf6d3f780fcb http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_621e2d609977738c89e2a7d6ec2df7f3 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_296b0596e23c8c535e8524f16bac88eb http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_43b17a42b4f1a97d2b03b42cfdcdd5a8 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d8ffc31b04bfaeb8fc89b28b66ec2684 |
| publicationDate | 2012-04-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | KR-20120034167-A |
| titleOfInvention | Methods and compositions for increasing trikogen efficacy of dermal cells |
| abstract | The present invention relates to methods and compositions for increasing trichogenity of cells in culture. One example is in vitro in the presence of an effective amount of one or more sonic hedgehog (Shh) pathway agonists to increase trichogenity of isolated mammalian dermal cells relative to untreated isolated mammalian dermal cells. It provides a method comprising culturing the isolated mammalian dermal cells. The cell culture optionally contains epidermal cells. Preferred Shh agonists include, but are not limited to, CUR-0236715 and CUR-0201365 which are commercially available from Curless Corporation. Trichogenity is measured using the Aderans Hair Patch Assay ™ . The cultured dermal cells may be maintained in the medium in the presence of one or more Shh agonists for at least 1 to 7 days or more prior to harvesting. Treated cultured dermal cells can be used to treat hair loss in mammalian subjects, preferably humans, by implanting them in an amount effective to induce hair follicle formation. |
| priorityDate | 2009-06-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 130.