http://rdf.ncbi.nlm.nih.gov/pubchem/patent/KR-20120033875-A
Outgoing Links
Predicate | Object |
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assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_cbffa3b81b3b862dc7220b5648f5f745 |
classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2035-00158 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B82Y15-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B82Y40-00 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-68 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-54346 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-552 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N21-84 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-52 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-68 |
filingDate | 2010-09-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_fa4e51f7977418fdb4bb0fc5fc901c08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3d91740b20224b5f09dd8fbf39d70746 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4ee5bed1651d0e397fc926cb8d09a353 |
publicationDate | 2012-04-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | KR-20120033875-A |
titleOfInvention | Probe protein-immobilized multi-spot copper-deposited nanostructure array biochips using copper binding peptides and a method of manufacturing the same |
abstract | The present invention relates to a multi-spot copper-deposited nanostructure array biochip in which a probe protein is immobilized using a copper binding peptide (CBP), and more particularly, to a substrate. A metal thin film layer including a formed thin metal layer, a multi-spot formed on the metal thin film layer, a nano-structure array layer having nanostructures arranged at regular intervals on each spot surface of the multi-spot, and a copper thin film layer formed on the nano-structure array layer Multi-spot copper-deposited nanostructure array biochips; A fusion protein combined with one or more CBP and probe protein on the surface of the multi-spot copper-deposited nanostructure array biochip is fixed on the surface of the copper layer to detect and quantify the interaction with the target biomaterial or the candidate target biomaterial. The present invention relates to a multi-spot copper-deposited nanostructure array biochip fixed with a probe protein using CBP. The multi-spot copper-deposited nanostructure array biochip having the probe protein fixed using the CBP according to the present invention may be combined with an optical characterization system including a light source, a detector, a spectrophotometer, and a computer, such as DNA, protein, and the like. It can be applied as an unlabeled optical biosensor that can detect the interaction of various biomaterials with high sensitivity, and can also be applied to on-site monitoring. In addition, the multi-spot copper-deposited nanostructure array biochip having the CBP-fixed probe protein according to the present invention can be fixed by selectively fixing the probe protein without chemical surface treatment process, thereby simplifying the chip fabrication process and the complex probe protein purification process. This eliminates the need for significant improvements in productivity and economics. |
isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-108895690-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-108895690-B http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2020080876-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9139914-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-107262735-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-107262735-B |
priorityDate | 2010-09-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 124.