| abstract |
The present invention describes peptide vaccines against cancer. In particular, it provides an epitope peptide derived from the TTK gene capable of inducing CTL. Also provided are antigen-presenting cells and isolated CTLs targeting the peptides as well as methods of inducing antigen-presenting cells, or CTLs. The present invention also provides a pharmaceutical composition comprising, as an active ingredient, a peptide derived from TTK or a polynucleotide encoding the peptide. Furthermore, the present invention provides for the treatment and / or prevention (ie, prevention) of cancer (tumor), and / or prevention of recurrence after its operation, as well as peptides derived from TTK, polynucleotides encoding such peptides, or Antigen-presenting cells presenting peptides, methods of inducing CTL using the pharmaceutical compositions of the invention, methods of inducing anti-tumor immunity are provided. |