| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_259697bb7506be6263dc8926165c2806 |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2320-50
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2310-3519
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2310-16
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2310-128 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-1131
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-1068
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P31-14 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-115
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-7105
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-63
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P31-14 |
| filingDate |
2010-09-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f13c91ae6b481017d315c140bd1dde5b
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_38b127a254c30b3a74a380d488ff15d4 |
| publicationDate |
2012-03-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
KR-20120029197-A |
| titleOfInvention |
Eptazyme that specifically releases antisense against micro RNA in HCV-infected cells and composition for treating HCV-related diseases using the same |
| abstract |
The present invention relates to a hammerhead ribozyme comprising an antisense against microRNA at a site released by self-cutting, with an aptamer for a substance encoded by HCV RNA, and a substance encoded by the HCV RNA bound to the aptamer. Eptazyme comprising an alternating module that induces self-cutting of the hammerhead ribozyme, and shows the effect of inhibiting the activity of micro RNA specifically in cells proliferating HCV The composition according to the present invention can be usefully used for the treatment of a disease associated with HCV. |
| priorityDate |
2010-09-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |