| abstract |
The present invention relates to a pharmaceutical composition and a veterinary composition for treating prion diseases, comprising at least one selected from the group consisting of cholesterol, HDL cholesterol and LDL cholesterol as an active ingredient. More specifically, cholesterol, HDL cholesterol or LDL cholesterol alleviates neuronal toxicity by modified prion protein peptides, thereby effectively inhibiting cell death and eliminating reactive oxygen species, thereby improving the treatment of prion diseases or improving prion disease. It can be used as an additive. |