http://rdf.ncbi.nlm.nih.gov/pubchem/patent/KR-20120022409-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_a251ae79dd7a008d95010b238c6aa1f8 |
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2501-65 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-7088 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-5073 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N5-0662 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-7088 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N5-0775 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-113 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-15 |
| filingDate | 2010-09-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_fb6d308d4b2017de67b5a64c1d2ab2bb http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6c36cad33329205c7fe2687e33b8bbea http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3e6611c44a3436ac9a5e83887678ebb6 |
| publicationDate | 2012-03-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | KR-20120022409-A |
| titleOfInvention | Composition for promoting proliferation, differentiation and senescence of mesenchymal stem cells using miRNA control |
| abstract | The present invention relates to a composition for promoting proliferation and differentiation of mesenchymal stem cells using miRNA regulation and inhibiting aging, and more specifically, proliferation and differentiation of stem cells containing an inhibitor of expression of miR-486 or miR-598 as an active ingredient. It relates to a composition for promoting and inhibiting aging. According to the present invention, by regulating the expression of specific miRNA, the expression of SIRT1, which plays an important role in the aging of human stromal cells (including MSC), can regulate cell growth, differentiation, inhibit cell aging, and in diabetic patients. Angiogenesis of mesenchymal stem cells with reduced function can be increased. Therefore, it can be used in the development of technology to control the proliferation, differentiation and therapeutic effect of mesenchymal stem cells using miRNA to control the expression of SIRT1. |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-108611320-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/KR-20140018448-A |
| priorityDate | 2010-09-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 810.