abstract |
The present invention relates to the embedding of live or dead microorganisms and / or bioactive substances in protective dry formulation matrices, wherein the formulation comprises bioactive microorganisms or substances, stabilizers and protective agents. The formulations are prepared by dispersing all solid components in a solution under or without applying a vacuum and cooling the solution to a temperature above its freezing temperature. The method includes first drying the formulation for a desired temperature and time, accelerated second drying under maximum vacuum and elevated temperature, to achieve the desired final water activity of the dry matter. |