abstract |
The present invention relates to a method for promoting the differentiation of nicotinic acid adenine dinucleotide phosphoric acid or derivatives thereof from keratinocytes to fibroblasts, and regenerating and improving skin barrier of a composition comprising NAADP or a derivative thereof, a stratum corneum such as psoriasis or atopic Pharmaceutical or cosmetic use for the prevention, amelioration or treatment of aberrant diseases, and the promotion of differentiation of isolated keratinocytes. |