| abstract |
Selenopheno triagene analogs, compositions thereof, tautomeric forms, stereoisomers, polymorphs, hydrates, solvates, and pharmaceutically acceptable salts and mixtures thereof are useful for the treatment of metastatic malignant melanoma and other cancers. Do. Said selenopheno triazane analogues have the general formula (I) or (II): Wherein the substituents R 1, R 2, R 3, R 6, and R 7 are as described in the specification. Other cancers that can be treated with these compounds include malignant melanoma, leukemia, lymphoma (Hodgkin's and non-Hodgkin's), sarcoma (Ewing's sarcoma), brain tumors, CNS metastatic cancer, glioma, breast cancer Carcinoma, prostate cancer, lung cancer (small cell and non-small cell), colon cancer, pancreatic cancer, head and neck cancer, and oropharyngeal squamous cell carcinoma. |