abstract |
The present invention provides novel and excellent methods for preventing and / or treating diseases related to cannabinoid type 2 receptors, based on agonist action on cannabinoid type 2 receptors. The present invention mainly relates to heterocyclic derivatives having two substituents, for example, pyrimidine-5-carboxylic acid amide derivatives having a substituted amino group at the 2-position, exhibiting a strong agonist action on cannabinoid type 2 receptors. The present invention was completed by finding that it can be a prophylactic and / or therapeutic agent for diseases related to cannabinoid type 2 receptors such as inflammatory diseases and pain. |