abstract |
The present invention relates to a solid dispersion having, but not limited to, microcrystalline plate structures having co-processed carbohydrates of different solubility and concentration. The solid dispersions, excipient systems and formulations of the present invention exhibit a high degree of compressibility and durability and are uniformly compacted when compressed into solid formulations, low crushability at low pressures, and / or a relatively constant low disintegration rate at different hardnesses. Seems. The solid dosage forms of the present invention show good functionality, disintegration and / or firmness. |