| abstract |
The present invention relates to novel substituted benzoxazoles, benzimidazoles, oxazolopyridine and imidazopyridine derivatives of formula (I): Where R 1 , R 2 , R 3 , R 4 , X, A 1 , A 2 , A 3 , A 4 , Y 1 , Y 2 , Y 3 and Z are as defined in the claims. The compounds according to the invention are useful as gamma secretase modulators. The invention also relates to a process for the preparation of the novel compounds, pharmaceutical compositions comprising said compounds as active ingredients and the use of said compounds as medicaments. |