| abstract |
A solid, continuous network comprising high mechanical strength excipients, the network also comprising voids, the voids interspersed in a mixture of the active ingredient and the film-forming agent, the voids being formed during the preparation of the composition. A sustained release pharmaceutical composition is provided. The compositions of the present invention can be used in particular in an oil-soluble combination comprising opioid analgesics that can be used for the treatment of chronic pain. |