| abstract |
The compound represented by the following general formula (1), or a pharmaceutically acceptable salt thereof, in any one of the following (I) or (II): (I) X: CH, N; R 1 : halogen; R 2 : H, halogen, CN, [2], [3], [8], [9], -O-alkyl, -O-saturated ring and the like [2]: -C (R C ) (R D ) (R E ) {R C -E : H, alkyl and the like} [3]: -N (R F ) (R G ) {R F -G : H, OH, amino, (hetero) aryl and the like} [8] : -C (= 0) R L {R L : alkyl, OH, alkoxy, amino, etc.] [9]: (substituted) phenyl; (II) X:> CC (═O) R B {R B : (substituted) amino, alkoxy, OH, etc.} R 1 : halogen; R 2 : H; R 3 : H, OH; R 4 -5: H, alkyl |