| abstract |
It is an object of the present invention to provide a disease, in particular osteoporosis therapeutic or preventive agents resulting from more than effective bone metabolism. Formula (Ⅰ) (Ⅰ) By using N-hydroxybenzamidine derivatives or salts thereof and active vitamin D or prodrugs thereof, a disease resulting from superior bone metabolic abnormalities, in particular osteoporosis treatment effect or prophylactic effect, is obtained as compared to single administration. . |