abstract |
The present invention relates to a tumor cell miRNA marker composition for anticancer agent screening, and more particularly, to a tumor cell miRNA marker composition for anticancer agent screening having any one of SEQ ID NOs: 146 to 171. According to the present invention, when resveratrol is treated to tumor cells, miRNAs whose expression changes more than two times were found, and miRNA target genes related to apoptosis, cell cycle regulation, and cell proliferation and differentiation were found. The association between tumor cell miRNA and resveratrol identified in the present invention will serve as an important basis for the study of anti-cancer mechanism of resveratrol in tumor cells. |