| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_a7de70cac0850545ae44679ec4ef53a6 |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A01K2267-0362
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2710-10343
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y02A50-30 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N9-1205
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Y207-01002
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P3-10
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P3-08
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P3-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K48-005
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K48-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-713
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-86
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-85
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-52
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-45
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-63 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K48-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-85
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-52
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-63 |
| filingDate |
2010-01-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_89db42a453fb2e652f0cbc281da43ef1 |
| publicationDate |
2011-09-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
KR-20110099057-A |
| titleOfInvention |
Human Glucokinase Mutant Coding Genes, Encoded Enzymes, Recombinant Vectors and Hosts, Pharmaceutical Compositions and Uses thereof, and Methods for Preventing and Treating Diseases |
| abstract |
The present invention provides a human glucokinase mutant coding gene, which includes a nucleotide sequence represented by SEQ ID NO: 2; Or the transcription frame encodes the same amino acid sequence as encoded by the transcription frame at positions 487-1884 of the nucleotide sequence represented by SEQ ID NO: 2, and the remaining portion other than the transcription frame is SEQ ID NO: It has the same nucleotide sequence as the nucleotide sequence shown by 2. The present invention also provides a glucokinase mutant expressing the gene, a recombinant vector comprising the gene, a host comprising the recombinant vector, a pharmaceutical composition comprising the same, uses thereof, and methods of preventing and treating diseases using the same. To provide. Since the activity of the glucokinase mutant expressed by the gene of the present invention is higher than that of the wild type glucokinase, a new method is provided for the prevention and treatment of blood glucose control or the prevention of glucose metabolism disorders, in particular the prevention and treatment of diabetes. |
| priorityDate |
2009-01-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |