abstract |
The present invention provides a tablet comprising a hygroscopic drug and having excellent disintegration, strength and drug stability. Specifically, the present invention provides a drug having an equilibrium moisture content of 10 to 20% under 75% relative humidity at 25 ° C, erythritol, mannitol, and an equilibrium moisture content of 5% under 75% relative humidity at 25 ° C. 20%, a disintegrating tablet containing hydroxypropyl cellulose having a viscosity of 100 to 2000 cps at 37 ° C in a 20% by mass aqueous solution, wherein the disintegrating tablet contains 15 to 50% by mass of the drug relative to the total amount of the disintegrating tablet. And disintegrating tablets having a porosity of 10 to 40%. |