| abstract |
The present invention provides a compound useful as an active ingredient of a pharmaceutical composition for treating a disease involving FAAH. MEANS TO SOLVE THE PROBLEM As a result of earnestly examining about the compound which has FAAH inhibitory activity, the piperazine-1-carboxyl which benzoimidazol-2-ylcarbonyl, benzofuran-2-ylcarbonyl, etc. couple | bond with piperazine 4-position The present invention was completed by confirming that the late compound has an excellent FAAH inhibitory activity, and further has an effective bladder dose increasing effect, a sleep disorder improving effect, an antidiuretic effect, and an analgesic effect on lower urinary tract pains such as bladder pain. The carbamate compound of the present invention has excellent FAAH inhibitory activity and can be used as a prophylactic and / or therapeutic agent for diseases involving FAAH, in particular nocturia, interstitial cystitis, circulating bladder syndrome or chronic non-bacterial prostatitis / chronic pelvic pain syndrome. have. |