| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_634f9eaf572cc875324ed64fa6f7bc77 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K49-06
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K51-0446
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K51-04
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D495-04 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D495-04
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K49-06
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K51-04 |
| filingDate |
2009-10-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7ac10ea383f5d83a0d7b1c714ee64b7c
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c2ca523b79d4c351b18c0a673c2b12f0
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9ed60ae27d8c18cf640f3a8c6d412a5d
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a6b1114c033450e0b9664281a9ea4e91
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9307e033be1bb6bd52e19b45cb8c12ac |
| publicationDate |
2011-06-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
KR-20110071072-A |
| titleOfInvention |
Indole Derivatives Suitable for Imaging Neuroinflammatory |
| abstract |
The present invention relates to in vivo imaging, in particular to in vivo imaging of peripheral benzodiazepines receptor (PBR). Tetracyclic indole in vivo imaging agents are provided that bind to PBR with high affinity, have good brain uptake after administration, and preferentially bind to tissues expressing high levels of PBR. The present invention also provides precursor compounds useful in the synthesis of the in vivo imaging agents of the invention, methods of synthesizing the in vivo imaging agents comprising the use of the precursor compounds, and kits for performing the methods. Cassettes for automated synthesis of in vivo imaging agents are also provided. The present invention also provides a radiopharmaceutical composition comprising the in vivo imaging agent of the invention, and a method of using said in vivo imaging agent. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/KR-20150030934-A |
| priorityDate |
2008-10-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |