| abstract |
The present invention relates to materials and methods for treating a human or animal with cognitive impairment. In one embodiment, the method comprises one or more inflammatory mediator (s), eg, ms-associated tyrosine kinase 3 (Flt3) ligand, interleukin-6 (IL-6), macrophage migration inhibitory factor (MIF), Interleukin-1 (IL-1), interleukin-3 (IL-3), erythropoietin (EPO), vascular endothelial growth factor A (VEGF-A), hypoxia-induced transcription factor (HIF-1 alpha), insulin Like growth factor-1 (IGF-1), tumor necrosis factor (TNF), granulocyte colony stimulating factor (G-CSF), granulocyte / macrophage colony stimulating factor (GM-CSF), macrophage colony stimulating factor (M-CSF ), Administering an effective amount of stem cell factor (SCF), darbepoetin (ARANESP), and metalloproteinase to an animal or human in need thereof. |