http://rdf.ncbi.nlm.nih.gov/pubchem/patent/KR-20110068979-A
Outgoing Links
Predicate | Object |
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assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_1d29f7ac2c7f9be9f7dae1a83bbb5c92 |
classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C2601-14 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07B61-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D417-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C69-65 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C67-347 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D213-30 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C67-347 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07B61-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C69-65 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D213-30 |
filingDate | 2009-09-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d759ee7d9b3cef593959d0fa2678310a |
publicationDate | 2011-06-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | KR-20110068979-A |
titleOfInvention | Method for producing a carbonyloxy compound |
abstract | The present invention synthesizes a diazonium salt by reacting an aniline compound with nitrite in the presence of an acid, and then reacts the resulting diazonium salt with an α, β-unsaturated carbonyloxy compound in the presence of a copper catalyst to produce a carbonyloxy compound. Provided is a method for producing a carbonyloxy compound, characterized in that a base having an acid dissociation index (pKa) of 25 ° C is 7 or less in a reaction between a diazonium salt and an α, β-unsaturated carbonyloxy compound at the time of preparation. do. According to the present invention, 2-bromo-3- {4- [2- (5-ethyl-2-pyridyl), which is an intermediate raw material of a therapeutic agent, shows an excellent effect on type 2 diabetes due to insufficient action of insulin. Methoxy] phenyl} methyl propionate and the like can be obtained with high efficiency and high purity. |
priorityDate | 2008-10-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 182.