| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_33f8096f7c6f74ac787c777aaf01104a |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-113
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61N5-10
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K48-00 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K39-395
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-68
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-7105 |
| filingDate |
2009-12-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c5a0677130346fe155a1921f6380a0d9
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_073284b0d87aa9b9f939f79fef2e0a0b
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4a48acaed8dc86c9d7e7863abe600952
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_57c954d3d796abea0f456adedc08cc7c |
| publicationDate |
2011-06-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
KR-20110062918-A |
| titleOfInvention |
How to increase the sensitivity of cancer cells to radiation by low expression of Dichibacterium-1 (DVII1) gene |
| abstract |
The present invention relates to a method of enhancing the sensitivity of cancer cells to radiation by the low expression of Dickkopf-1 (DKK1) gene, and more specifically, to increase the expression of DKK1 in lung cancer cell lines to increase resistance to radiation stress. Since the sensitivity of cancer cells to radiation stress is enhanced by inhibiting the expression of DKK1 to promote apoptosis, the radiation sensitizer containing the DKK1 protein expression or activity inhibitor of the present invention inhibits the growth of cancer cells, By increasing sensitivity to stress to maximize cell death, when used in combination with radiation therapy, it can be used very effectively in chemotherapy. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2022518430-A |
| priorityDate |
2009-12-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |