http://rdf.ncbi.nlm.nih.gov/pubchem/patent/KR-20110049740-A
Outgoing Links
Predicate | Object |
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assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_0e8d6d46c7439444f2ee053109f024e5 |
classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12R2001-465 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-36 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12P17-188 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N1-20 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N1-205 |
classificationIPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12R1-465 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N1-20 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-31 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12P17-16 |
filingDate | 2010-11-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8b978e0ea4472d7a7b17725282c52e57 |
publicationDate | 2011-05-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | KR-20110049740-A |
titleOfInvention | Tacrolimus producing strains and tacrolimus biosynthetic genes obtained therefrom |
abstract | The present invention provides a novel Streptomyces sp. Which can produce tacrolimus FK506, which is known to have immunosuppressive activity, with high efficiency. MJM7001 strain and tacrolimus biosynthetic gene obtained from the strain, the tacrolimus producing strain according to the present invention is capable of mass production of tacrolimus in high efficiency, compared to the conventional tacrolimus producing strain, high purity Since it can be isolated, it can be useful for the production of immunosuppressive agents used for the prevention and treatment of rejection by organ transplantation, graft-versus-host disease, autoimmune disease, infectious disease, etc. Tacrolimus biosynthesis genes isolated from them may suggest new possibilities for industrial strain improvement methods suitable for the optimization and mass production of industrially and medically useful bioactive substances. |
priorityDate | 2009-11-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 1003.